Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable language for describing phenotypes and their genomic and environmental contexts is perhaps the most pressing scientific bottleneck to integration across many key fields in biology, including genomics, systems biology, development, medicine, evolution, ecology, and systematics. Here we survey the current phenomics landscape, including data resources and handling, and the progress that (...) has been made to accurately capture relevant data descriptions for phenotypes. We present an example of the kind of integration across domains that computable phenotypes would enable, and we call upon the broader biology community, publishers, and relevant funding agencies to support efforts to surmount today's data barriers and facilitate analytical reproducibility. (shrink)

Context — Children and adults with psychopathic traits and conduct or oppositional defiant disorder demonstrate poor decision making and are impaired in reversal learning. However, the neural basis of this impairment has not previously been investigated. Furthermore, despite high comorbidity of psychopathic traits and attention deficit/hyperactivity disorder, to our knowledge, no research has attempted to distinguish neural correlates of childhood psychopathic traits and attention-deficit/hyperactivity disorder. Objective—To determine the neural regions that underlie the reversal learning impairments in children with psychopathic traits (...) plus conduct or oppositional defiant disorder. Design — Case-control study. Setting — Government clinical research institute. Participants — Forty-two adolescents aged 10 to 17 years: 14 with psychopathic traits and oppositional defiant disorder or conduct disorder, 14 with attention-deficit/hyperactivity disorder only, and 14 healthy controls. Main Outcome Measure — Blood oxygenation level–dependent signal as measured via functional magnetic resonance imaging during a probabilistic reversal task. Results — Children with psychopathic traits showed abnormal responses within the ventromedial prefrontal cortex (Brodmann area 10) during punished reversal errors compared with children wit hattention deficit/hyperactivity disorder and healthy children (P < .05 corrected for multiple comparisons). Conclusions — To our knowledge, this study provides the first evidence of abnormal ventromedial prefrontal cortex responsiveness in children with psychopathic traits and demonstrates this dysfunction was not attributable to comorbid attention-deficit/hyperactivity disorder. These findings suggest that reversal learning impairments in patients with developmental psychopathic traits relate to abnormal processing of reinforcement information. (shrink)

Traditionally pragmatists have been favorably disposed to improving our understanding of agency and ethics through the use of empirical research. In the last two decades simulation theory has been championed in certain cognitive science circles as a way of explaining how we attribute mental states and predict human behavior. Drawing on research in psychology and neuroscience, Alvin I. Goldman and Robert M. Gordon have not only used simulation theory to discuss how we “mindread”, but have suggested that the theory (...) has implications for ethics. The limitations of simulation theory for “mindreading” and ethics are addressed in this article from an interactionist or neo-Meadian pragmatic perspective. To demonstrate the limitations of simulation theory scenes from the television show Mad Men are used as “thought-experiments”. (shrink)

In this paper we show how a realistic normative democratic theory can work within the constraints set by the most pessimistic empirical results about voting behaviour and elite capture of the policy process. After setting out the empirical evidence and discussing some extant responses by political theorists, we argue that the evidence produces a two-pronged challenge for democracy: an epistemic challenge concerning the quality and focus of decision-making and an oligarchic challenge concerning power concentration. To address the challenges we then (...) put forward three main normative claims, each of which is compatible with the evidence. We start with a critique of the epistocratic position commonly thought to be supported by the evidence. We then introduce a qualified critique of referenda and other forms of plebiscite, and an outline of a tribune-based system of popular control over oligarchic influence on the policy process. Our discussion points towards a renewal of democracy in a plebeian but not plebiscitarian direction: Attention to the relative power of social classes matters more than formal dispersal of power through voting. We close with some methodological reflections about the compatibility between our normative claims and the realist program in political philosophy. (shrink)

Розкрито сутність поняття «рейтинг». Доведено значущість рейтингової оцінки для суб’єктів фінансового ринку, зокрема для страхових компаній, потенційних страхувальників, інвесторів та кредиторів.

This paper aims to provide an overview of the conceptual terrain of what we call conative accounts of personal identity. These are views according to which the same-person relation in some sense depends on a range of broadly conative phenomena, especially desires, behaviours and conventions. We distinguish views along three dimensions: what role the conations play, what kinds of conations play that role, and whether the conations that play that role are public or private. We then offer a more detailed (...) consideration of direct private conativism—the version of conativism that we favour—before considering how conativists ought respond to a general worry, according to which any conativist view will lead us to be radically pluralist about persons. (shrink)

The idea that there could be spatially extended mereological simples has recently been defended by a number of metaphysicians (Markosian 1998, 2004; Simons 2004; Parsons (2000) also takes the idea seriously). Peter Simons (2004) goes further, arguing not only that spatially extended mereological simples (henceforth just extended simples) are possible, but that it is more plausible that our world is composed of such simples, than that it is composed of either point-sized simples, or of atomless gunk. The difficulty for these (...) views lies in explaining why it is that the various sub-volumes of space occupied by such simples, are not occupied by proper parts of those simples. Intuitively at least, many of us find compelling the idea that spatially extended objects have proper parts at every sub-volume of the region they occupy. It seems that the defender of extended simples must reject a seemingly plausible claim, what Simons calls the geometric correspondence principle (GCP): that any (spatially) extended object has parts that correspond to the parts of the region that it occupies (Simons 2004: 371). We disagree. We think that GCP is a plausible principle. We also think it is plausible that our world is composed of extended simples. We reconcile these two notions by two means. On the one hand we pay closer attention to the physics of our world. On the other hand, we consider what happens when our concept of something—in this case space—contains elements not all of which are realized in anything, but instead key components are realized in different features of the world. (shrink)

This paper is concerned with the relation between two notions: that of two solutions or models of a theory being related by a symmetry of the theory and that of solutions or models being physically equivalent. A number of authors have recently discussed this relation, some taking an optimistic view, on which there is a suitable concept of the symmetry of a theory relative to which these two notions coincide, others taking a pessimistic view, on which there is no such (...) concept. The present paper arrives at a cautiously pessimistic conclusion. (shrink)

A number of recent theories of quantum gravity lack a one-dimensional structure of ordered temporal instants. Instead, according to many of these views, our world is either best represented as a single three-dimensional object, or as a configuration space composed of such three-dimensional objects, none of which bear temporal relations to one another. Such theories will be empirically self-refuting unless they can accommodate the existence of conscious beings capable of representation. For if representation itself is impossible in a timeless world, (...) then no being in such a world could entertain the thought that a timeless theory is true, let alone believe such a theory or rationally believe it. This paper investigates the options for understanding representation in a three-dimensional, timeless, world. Ultimately it concludes that the only viable option is one according to which representation is taken to be deeply non-naturalistic. Ironically then we are left with two seemingly very unattractive options. Either a very naturalistic motivation—taking seriously a live view in fundamental physics—leads us to a very non-naturalistic view of the mental, or else views in the philosophy of mind partly dictate what is an acceptable theory in physics. (shrink)

Intuitively, a classical field theory is background-in- dependent if the structure required to make sense of its equations is itself subject to dynamical evolution, rather than being imposed ab initio. The aim of this paper is to provide an explication of this intuitive notion. Background-independence is not a not formal property of theories: the question whether a theory is background-independent depends upon how the theory is interpreted. Under the approach proposed here, a theory is fully background-independent relative to an interpretation (...) if each physical possibility corresponds to a distinct spacetime geometry; and it falls short of full background-independence to the extent that this condition fails. (shrink)

The direct social perception thesis claims that we can directly perceive some mental states of other people. The direct perception of mental states has been formulated phenomenologically and psychologically, and typically restricted to the mental state types of intentions and emotions. I will compare DSP to another account of mindreading: dual process accounts that posit a fast, automatic “Type 1” form of mindreading and a slow, effortful “Type 2” form. I will here analyze whether dual process accounts’ Type 1 mindreading (...) serves as a rival to DSP or whether some Type 1 mindreading can be perceptual. I will focus on Apperly and Butterfill’s dual process account of mindreading epistemic states such as perception, knowledge, and belief. This account posits a minimal form of Type 1 mindreading of belief-like states called registrations. I will argue that general dual process theories fit well with a modular view of perception that is considered a kind of Type 1 process. I will show that this modular view of perception challenges and has significant advantages over DSP’s phenomenological and psychological theses. Finally, I will argue that if such a modular view of perception is accepted, there is significant reason for thinking Type 1 mindreading of belief-like states is perceptual in nature. This would mean extending the scope of DSP to at least one type of epistemic state. (shrink)

This paper proffers an account of why interdisciplinary research on, inter alia, the nature of time can be fruitful even if the disciplines in question have different explanatory pro-jects. We suggest that the special sciences perform a subject setting role for lower-level disciplines such as physics. In essence, they tell us where, amongst a theory of the physical world, we should expect to locate phenomena such as temporality; they tell us what it would take for there to be time. Physical (...) theory tells us whether there is anything like that in the world and what its hidden nature is. Only working in tandem can physics and the special sciences locate and describe the phenomenon that is time. (shrink)

Martin Heidegger devotes extensive discussion to medieval philosophers, particularly to their treatment of Truth and Being. On both these topics, Heidegger accuses them of forgetting the question of Being and of being responsible for subjugating truth to the modern crusade for certainty: ‘truth is denied its own mode of being’ and is subordinated ‘to an intellect that judges correctly’. Though there are some studies that discuss Heidegger’s debt to and criticism of medieval thought, particularly that of Thomas Aquinas, there is (...) no constructive reply to his assertions. As a result, Heidegger’s critique had an unprecedented effect on the credibility of medieval philosophy, whereby great portions of the philosophical community dismiss it altogether as an illegitimate Onto‐Theology. It is the aim of this study to offer a constructive reply that will fundamentally grapple with these allegations. By constructive reply we mean not only a reply that avoids the problems Heidegger raises regarding existence, essence and truth, but more importantly, one that uses Heidegger’s criticism in order to present a more insightful account of these notions. The present study is composed of two parts where the second serves as a sort of addendum. The first part, the core of this study, is an attempt to develop an understanding of the distinction between essence and existence that, on the one hand, accords with Heidegger’s criticism while on the other hand advances our understanding of how we think and understand reality. After presenting Heidegger’s depiction of Aquinas’s distinction between essence and existence (esse) as a real distinction, the study will present several views propounded by scholars of Aquinas regarding the status of this distinction. It will be argued that it is not clear whether the distinction is real, formal or conceptual, and that different types of distinction are applied in different places, particularly in regard to the phantasm that Aquinas considers essential to the human act of thinking. The second part diverges from the first part and focuses on Heidegger’s criticism of Aquinas’s conception of truth as adequation, i.e., what it is that grounds the possibility of truth as adequation. This divergence is necessary in order to present a full metaphysical response to Heidegger’s criticism. Since the aim of the present study is to argue that Aquinas’s philosophical system can contend with Heidegger’s criticism, a partial reply would greatly diminish its effectiveness. (shrink)

This paper is concerned with learners who aim to learn patterns in infinite binary sequences: shown longer and longer initial segments of a binary sequence, they either attempt to predict whether the next bit will be a 0 or will be a 1 or they issue forecast probabilities for these events. Several variants of this problem are considered. In each case, a no-free-lunch result of the following form is established: the problem of learning is a formidably difficult one, in that (...) no matter what method is pursued, failure is incomparably more common that success; and difficult choices must be faced in choosing a method of learning, since no approach dominates all others in its range of success. In the simplest case, the comparison of the set of situations in which a method fails and the set of situations in which it succeeds is a matter of cardinality (countable vs. uncountable); in other cases, it is a topological matter (meagre vs. co-meagre) or a hybrid computational-topological matter (effectively meagre vs. effectively co-meagre). (shrink)

Under so-called primitive ontology approaches, in fully describing the history of a quantum system, one thereby attributes interesting properties to regions of spacetime. Primitive ontology approaches, which include some varieties of Bohmian mechanics and spontaneous collapse theories, are interesting in part because they hold out the hope that it should not be too difficult to make a connection between models of quantum mechanics and descriptions of histories of ordinary macroscopic bodies. But such approaches are dualistic, positing a quantum state as (...) well as ordinary material degrees of freedom. This paper lays out and compares some options that primitive ontologists have for making sense of the quantum state. (shrink)

Psychological construction represents an important new approach to psychological phenomena, one that has the promise to help us reconceptualize the mind both as a behavioral and as a biological system. It has so far been developed in the greatest detail for emotion, but it has important implications for how researchers approach other mental phenomena such as reasoning, memory, and language use. Its key contention is that phenomena that are characterized in (folk) psychological vocabulary are not themselves basic features of the (...) mind, but are constructed from more basic psychological operations. The framework of mechanistic explanation, currently under development in philosophy of science, can provide a useful perspective on the psychological construction approach. A central insight of the mechanistic account of explanation is that biological and psychological phenomena result from mechanisms in which component parts and operations do not individually exhibit the phenomena of interest but function together in an orchestrated and sometimes in a complex dynamical manner to generate it. While at times acknowledging the compatibility of the mechanist approach with constructionist approach (Lindquist, Wager, Kober, Bliss-Moreau, & Barrett, 2012), proponents of the constructionist approach have at other times pitched their approach as anti-mechanist. For example, Barrett (2009) claims that the psychological constructionist approach rejects machines as the primary metaphor for understanding the mind, instead favoring a recipe metaphor; constructionism also purportedly rejects the “mechanistic” picture of causation, which it portrays as linear or sequential in nature (see also Barrett, Wilson-Mendenhall, & Barsalou, in press). While some mechanistic accounts do fit this description, we will see that the mechanisms generating phenomena can be complex and dynamic, producing phenomena far less stereotypic and more adaptive than people often associate with machines. Our goal, however, is not just to render constructionism and mechanism compatible. Philosophers of science have been examining the nature of mechanistic explanation in biology with the goal of gaining new insights into the operation of science. We will identify some of the places where the mechanistic account can shed new light on the constructionist project. (shrink)

In this paper we argue that reflection on the patterns of practical concern that agents like us exhibit strongly suggests that the same person relation comes in continuous degrees rather than being an all or nothing matter. We call this the SP-degree thesis. Though the SP-degree thesis is consistent with a range of views about personal-identity, we argue that combining desire-first approaches to personal-identity with the SP-degree thesis better explains our patterns of practical concern, and hence gives us reason to (...) endorse such an approach. We then argue that the combination of the SP-degree thesis and the desire-first approach are best modelled by a stage-theoretic view of persistence according to which temporal counterpart relations are non-symmetric relations that come in continuous degrees. Ultimately, we think that the overall appeal of this package of views provides reason to accept the package: reasons that outstrip the reasons we have to endorse any particular member of the package. (shrink)

At 435c-d and 504b ff., Socrates indicates that there is a "longer and fuller way" that one must take in order to get "the best possible view" of the soul and its virtues. But Plato does not have him take this "longer way." Instead Socrates restricts himself to an indirect indication of its goals by his images of sun, line, and cave and to a programmatic outline of its first phase, the five mathematical studies. Doesn't this pointed restraint function as (...) a provocation, moving us to want to begin the "longer way" and to make use of its conceptual resources to rethink Socrates' images? I begin by finding a double movement in the complex trajectory of the five studies: they both guide the soul in the "turn away from what is coming to be ... [to] what is" (518c) and, at the same time, lead the soul back, albeit in the medium of pure intelligibility, to the sensible world; for the pure figures and ratios that they disclose constitute the core structures of sensible things. I then draw on what Socrates says about geometry and harmonics to address three fundamental questions that he leaves open: the nature of the Good in its responsibility for truth and for the being of the forms; the relations of forms, mathematicals, and sensibles as these are disclosed by dialectic; and the bearing of the philosopher's discovery of the Good on his disposition towards his community and the task of ruling. I close by marking six sets of further questions that these reflections bequeath for dialogues to come. (shrink)

The paper by Monteiro, Musten and Compson (2014) is to be commended for providing a comprehensive discussion of the compatibility issues arising from the integration of mindfulness – a 2,500-year-old Buddhist practice – into research and applied psychological domains. Consistent with the observations of various others (e.g., Dunne, 2011; Kang & Whittingham, 2010), Monteiro and colleagues have not only highlighted that there are differences in how Buddhism and contemporary mindfulness interventional approaches interpret and contextualize mindfulness, but there are also differing (...) interpretations of mindfulness within Buddhism. These apparent differences within Buddhism are arguably more noticeable when making comparisons across Buddhist vehicles (i.e., Theravada, Mahayana, Vajrayana), but to a lesser extent intra-vehicular differences can also be said to exist (i.e., differences between Buddhist traditions of the same vehicle). This commentary investigates the validity of some of these different Buddhist constructions of mindfulness, and then discusses how a better understanding of their scriptural and conceptual soundness (or lack thereof) may help to reconcile some of the actual and perceived incompatibility between Buddhist practice and contemporary secular mindfulness-based approaches. (shrink)

A close reading of the poem of Parmenides, with focal attention to the way the proem situates Parmenides' insight in relation to Hesiod and Anaximander and provides the context for the thought of "... is". I identify three pointed ambiguities, in the direction of the journey to the gates of the ways of Night and Day, in the way the gates swing open before the waiting traveler, and in the character of the "chasm" that their opening makes, and I suggest (...) ways in which these ambiguities at once complicate and determine the significance of the thought of "... is" and its implications for the status of the opinions of mortals. (shrink)

Metaphysics is largely an a priori business, albeit a business that is sensitive to the findings of the physical sciences. But sometimes what the physical sciences tell us about our own world underdetermines what we should think about the metaphysics of how things actually are, and even how they could be. This chapter has two aims. The first is to defend a particular conception of the methodology of a priori metaphysics by, in part, exemplifying that methodology and revealing its results. (...) The second is to present a new account of holes. These two aims dovetail nicely. We are independently interested in providing a better analysis of the concept <hole> that yields a more plausible metaphysical story about holes. But focusing on holes is also a good way to explore the methodology we endorse: for this is an area of metaphysics that is sufficiently self-contained and narrow in focus that it provides a manageable case study, while at the same time raising interesting and deep issues about the nature of space. Ultimately we defend a new, functionalist, analysis of holes, which, unlike its rivals, neither misidentifies nor renders us implausibly eliminativist about holes under various different metaphysical suppositions about the nature of space. In the process, we set out the complex relations between the intension of “hole,” and its extension at various worlds under different suppositions about the nature of space. In explicating these relations our account exemplifies what we take to be the core methodology in a priori metaphysics. (shrink)

A discussion of the sense in which reality is mind-dependent for Kant and for David Lewis. Plus a lot about space-aliens (and a bit about pimple-worms).

Many naive realists endorse a negative disjunctivist strategy in order to deal with the challenge presented by the possibility of phenomenologically indistinguishable halucination. In the first part of this paper I argue that this approach is methodologically inconsistent because it undercuts the phenomenological motivation that underlies the the appeal of naive realism. In the second part of the paper I develop an alternative to the negative disjunctivist account along broadly Meinongian lines. In the last section of this paper I consider (...) and evaluate a somewhat similar but rival view of hallucination developed by Mark Johnston. (shrink)

In recent decades, economists have played an active role in shaping public policy by publicly recommending the adoption of certain policies. These recommendations are often based on normative assumptions that are not the product of economic analysis; nor are they shared by the laypeople to whom these recommendations are made. Inducing people to adopt public policies for reasons that are neither the product of expertise, nor shared by the people, is a form of manipulation that violates the ideals of a (...) liberal democratic society. Thus, the economists’ recommendations constitute an abuse of their expertise. (shrink)

A piece of folklore enjoys some currency among philosophical Bayesians, according to which Bayesian agents that, intuitively speaking, spread their credence over the entire space of available hypotheses are certain to converge to the truth. The goals of the present discussion are to show that kernel of truth in this folklore is in some ways fairly small and to argue that Bayesian convergence-to-the-truth results are a liability for Bayesianism as an account of rationality, since they render a certain sort of (...) arrogance rationally mandatory. (shrink)

Ismael aims for an understanding of the nature of an embedded perspective of agents in a world. If successful, this would explain a cluster of ways in which from an embedded perspective, we experience the world in an array of temporally asymmetric ways. Moreover, these are ways that have led many philosophers to rather metaphysically inflationary views about the nature of time, according to which time itself really is dynamical, and is characterized by the movement of an objectively (i.e., non-perspectival) (...) present. Ismael aims to explain these features of our experience without positing any such metaphysical picture. She argues that there are constraints which prevent us from taking this Olympian conception of the world and our place in it, and that these, jointly, explain why we experience the world in these temporally asymmetric ways. We take up two related questions. First, what it would mean to say that these constraints are not merely epistemic, and second, how far these constraints get us in explaining why we experience the world in these ways. (shrink)

Future-bias is the preference, all else being equal, for negatively valenced events be located in the past rather than the future, and positively valenced ones to be located in the future rather than the past. Strong risk aversion is the preference to pay some cost to mitigate the badness of the worst outcome. People who are both strongly risk averse and future-biased can face a series of choices that will guarantee them more pain, for no compensating benefit: they will be (...) pain pumped. Thus, combining these preferences is rationally impermissible. Dougherty (2011) argues that this gives us reason to think that future-bias is rationally impermissible. This argument, and a similar one presented by Greene and Sullivan (2015), relies on the idea that if several preferences are not rationally combinable, then in the absence of some explanation of why they are not combinable, we should conclude that (at least) one of them is rationally impermissible. We take up this question by, inter alia, reflecting on the empirical results of a study we ran that probes people’s risk averse and future-biased preferences. We argue that the data, in conjunction with other considerations, suggests that we should not infer from the irrationality of the combination of these preferences to the irrationality of one of the preferences singly. We also argue that given the descriptive data about these preferences, there is no reason to think that, if one of them is rationally impermissible, then it is future-bias. (shrink)

Metaphysics is largely an a priori business, albeit a business that is sensitive to the findings of the physical sciences. This chapter has two aims. The first is to defend a particular conception of the methodology of a priori metaphysics by, in part, exemplifying that methodology and revealing its results. The second is to present a new account of holes. These two aims dovetail nicely. The chapter provides a better analysis of the concept ′hole′ that yields a more plausible metaphysical (...) story about holes. The authors defend a new, functionalist, analysis of holes, which, unlike its rivals, neither misidentifies nor renders them implausibly eliminativist about holes under various different metaphysical suppositions about the nature of space. In the process, the authors set out the complex relations between the intension of "hole," and its extension at various worlds under different suppositions about the nature of space. (shrink)

The orgulity objection of Belot (2013) is recast in the form of a decision problem.

Schervish (1985b) showed that every forecasting system is noncalibrated for uncountably many data sequences that it might see. This result is strengthened here: from a topological point of view, failure of calibration is typical and calibration rare. Meanwhile, Bayesian forecasters are certain that they are calibrated---this invites worries about the connection between Bayesianism and rationality.

It is widely thought that chance should be understood in reductionist terms: claims about chance should be understood as claims that certain patterns of events are instantiated. There are many possible reductionist theories of chance, differing as to which possible pattern of events they take to be chance-making. It is also widely taken to be a norm of rationality that credence should defer to chance: special cases aside, rationality requires that one's credence function, when conditionalized on the chance-making facts, should (...) coincide with the objective chance function. It is a shortcoming of a theory of chance if implies that this norm of rationality is unsatisfiable. The primary goal of this paper is to show, on the basis of considerations concerning computability and inductive learning, that this shortcoming is more common than one would have hoped. (shrink)

Tracking theories see knowledge as a relation between a subject’s belief and the truth, where the former is responsive to the latter. This relationship involves causation in virtue of a sensitivity condition, which is constrained by an adherence condition. The result is what I call a stable causal relationship between a fact and a subject’s belief in that fact. I argue that when we apprehend the precise role of causation in the theory, previously obscured problems pour out. This paper presents (...) thirteen distinct and original counterexamples to Nozick’s tracking theory—many of which also constitute problems for more recent tracking theories. I begin by discussing how tracking relates to causation: Nozick invokes causation through conditions similar to those of Lewisian causal dependence. As a result, when causal dependence is not necessary for causation, Nozick fails to identify knowledge. I then address the inability of causation to capture epistemically important concepts, such as justification and truth. I conclude by discussing the underlying asymmetries between causation and knowledge that undermine any attempt to reduce knowledge to a purely metaphysical relation. (shrink)

Like Lewis, many philosophers hold reductionist accounts of chance (on which claims about chance are to be understood as claims that certain patterns of events are instantiated) and maintain that rationality requires that credence should defer to chance (in the sense that under certain circumstances one's credence in an event must coincide with the chance of that event). It is a shortcoming of an account of chance if it implies that this norm of rationality is unsatisfiable by computable agents. This (...) shortcoming is more common than one might have hoped. (shrink)

Change is the fundamental idea of evolution. Explaining the extraordinary biological change we see written in the history of genomes and fossil beds is the primary occupation of the evolutionary biologist. Yet it is a surprising fact that for the majority of evolutionary research, we have rarely studied how evolution typically unfolds in nature, in changing ecological environments, over space and time. While ecology played a major role in the eventual acceptance of the population genetic viewpoint of evolution in the (...) synthetic era (circa 1918-1956), it held a lesser role in the development of evolutionary theory until the 1980s, when we began to systematically study the evolutionary dynamics of natural populations in space and time. As a result, early evolutionary theory was initially constructed in an abstract vacuum that was unrepresentative of evolution in nature. The subtle synthesis between ecology with evolutionary biology (eco-evo synthesis) over the past 40 years has progressed our knowledge of natural selection dynamics as they are found in nature, thus revealing how natural selection varies in strength, direction, form, and, more surprisingly, level of biological organization. Natural selection can no longer be reduced to lower levels of biological organization (i.e., individuals, selfish genes) over shorter timescales but should be expanded to include adaptation at higher levels and over longer timescales. Long-term and/or emergent evolutionary phenomena, such as multilevel selection or evolvability, have thus become tenable concepts within an evolutionary biology that embraces ecology and spatiotemporal change. Evolutionary biology is currently suspended at an intermediate stage of scientific progress that calls for the organization of all the recent knowledge revealed by the eco-evo synthesis into a coherent and unified theoretical framework. This is where philosophers of biology can be of particular use, acting as a bridge between the subdisciplines of biology and inventing new theoretical strategies to organize and accommodate the recent knowledge. Philosophers have recommended transitioning away from outdated philosophies that were originally derived from physics within the philosophical zeitgeist of logical positivism (i.e., monism, reductionism, and monocausation) and toward a distinct philosophy of biology that can capture the natural complexity of multifaceted biological systems within diverse ecosystems—one that embraces the emerging philosophies of pluralism, emergence, and multicausality. Therefore, I see recent advances in ecology, evolutionary biology, and the philosophy of biology as laying the groundwork for another major biological synthesis, what I refer to as the Second Synthesis because, in many respects, it is analogous to the aims and outcomes of the first major biological synthesis (but is notably distinct from the inorganic and contrived progressive movement known as the extended evolutionary synthesis). With the general development of a distinctive philosophy of science, biology has rightfully emerged as an autonomous science. Thus, while the first synthesis legitimized biology, the Second Synthesis autonomized biology and afforded biology its own philosophy, allowing biology to finally realize its full scientific potential. (shrink)

Advances in the empirical sectors of biology are beginning to reveal evolvability as a major evolutionary process. Yet evolvability’s theoretical role is still intensely debated. Since its inception nearly thirty years ago, the evolvability research front has put a strong emphasis on the non-genetic mechanisms that influence the short-term evolvability of individuals within populations by causing phenotypic heterogeneity, such as developmental trait plasticity, phenotypic plasticity, modularity, the G-P map, robustness, and/or epigenetic variation. However, genetic evolvability mechanisms such as mutation or (...) recombination have a deeper history in evolutionary thought that is often overlooked by those in the evolvability research front, with recent evidence suggesting that species switch to genetic evolvability mechanisms when short-term evolvability strategies fail to relieve selective pressures. For this reason, a causal distinction must be made between genetic evolvability and the more recently emphasized non-genetic (or evo-devo) evolvability to allow for its maturation as a central explanatory concept. I conclude by arguing that the anachronisms of the scientific process are the main culprit behind recent divisions in biology and likely beyond. To streamline theoretical progress, we need to build a new science with new underlying philosophies like restricted pluralism. (shrink)

Harold Noonan has recently argued (2003) that one of Lewis’s (1983: 76– 77) arguments for the view that objects persist by perduring is flawed. Lewis’s argument can be divided into two main sections, the first of which attempts to show that it is possible that there exists a world of temporal parts or stages, and the second, which attempts to show that our world is such a world. Noonan claims that there is a flaw in each of these two stages.We (...) argue to the contrary. (shrink)

The twin goals of this essay are: to investigate a family of cases in which the goal of guaranteed convergence to the truth is beyond our reach; and to argue that each of three strands prominent in contemporary epistemological thought has undesirable consequences when confronted with the existence of such problems. Approaches that follow Reichenbach in taking guaranteed convergence to the truth to be the characteristic virtue of good methods face a vicious closure problem. Approaches on which there is a (...) unique rational doxastic response to any given body of evidence can avoid incoherence only by rendering epistemology a curiously limited enterprise. Bayesian approaches rule out humility about one’s prospects of success in certain situations in which failure is typical. (shrink)

Psychological approaches to treating mental illness or improving psychological wellbeing are invariably based on the explicit or implicit understanding that there is an intrinsically existing ‘self’ or ‘I’ entity. In other words, regardless of whether a cognitive-behavioural, psychodynamic, or humanistic psychotherapy treatment model is employed, these approaches are ultimately concerned with changing how the ‘I’ relates to its thoughts, feelings, and beliefs, and/or to its physical, social, and spiritual environment. Although each of these psychotherapeutic modalities have been shown to have (...) utility for improving psychological health, there are inevitably limitations to their effectiveness and there will always be those individuals for whom they are incompatible. Given such limitations, research continuously attempts to identify and empirically validate more effective, acceptable and/or diverse treatment approaches. One such approach gaining momentum is the use of techniques that derive from Buddhist contemplative practice. Although mindfulness is arguably the most popular and empirically researched example, there is also growing interest into the psychotherapeutic applications of Buddhism’s ‘non-self’ ontological standpoint (in which ontology is basically the philosophical study of the nature or essence of being, existence, or reality). (shrink)

There are many parts of science in which a certain sort of underdetermination of theory by evidence is known to be common. It is argued that reflection on this fact should serve to shift the burden of proof from scientific anti-realists to scientific realists at a crucial point in the debate between them.

A close exegesis of the principles of the so-called "god-given method" of dialectic in the Philebus (16bff., 23cff.) and an account of the division of the fifteen kinds of art that "care" for the well-formed city in the Statesman (287bff., 303cff.). I show how this division conforms to and, so, illustrates the "god-given method.".

Dmitri Nikulin extends his earlier study of oral dialogue (On Dialogue [Lexington, 2006]) to an investigation of dialectic, moving from a narrative of its development in Plato and the history of philosophy (ch.s 1-3) through a renewed phenomenological account of oral dialogue (ch.s 4-5) to a critique, from the perspective of oral dialogue, of the limitations of written dialectic (ch. 6). I take up some of the provocations of his bold and open-ended argument. Does his own “writing against writing” constitute (...) a performative contradiction, and if so, does this attest his critique of the limitations of dialectic or exhibit, in the elicitative force of its irony, the transcending of these limitations? How, if at all, may we reconcile Nikulin’s radical claim that oral dialogue is the very mode of being human with the drive of the turn to written dialectic to understand being itself and its relation to being human? Just insofar as the virtues distinctive of written dialectic — above all, precision, systematic elaboration, and universality — move the philosopher to suspend oral dialogue in its essential attention to a particular other and to the “who” that one emerges as for this other, may this very suspension also constitute a phase within ongoing oral dialogue? Are the last words of the “(Dialectical) Conclusion” with which Nikulin paradoxically closes his critique of dialectic really just the opening words of a conversation that the attentive reader’s very being moves him to pursue? (shrink)

Objectives. The purpose of this study was to conduct the first randomized controlled trial (RCT) to evaluate the effectiveness of a second-generation mindfulness-based intervention (SG-MBI) for treating fibromyalgia syndrome (FMS). Compared to first generation mindfulness-based interventions, SG-MBIs are more acknowledging of the spiritual aspect of mindfulness. Design. A RCT employing intent-to-treat analysis. Methods. Adults with FMS received an 8-week SG-MBI known as meditation awareness training (MAT; n = 74) or an active control intervention known as cognitive behaviour theory for groups (...) (n = 74). Assessments were performed at pre-, post-, and 6-month follow-up phases. Results. Meditation awareness training participants demonstrated significant and sustained improvements over control group participants in FMS symptomatology, pain perception, sleep quality, psychological distress, non-attachment (to self, symptoms, and environment), and civic engagement. A mediation analysis found that (1) civic engagement partially mediated treatment effects for all outcome variables, (2) non-attachment partially mediated treatment effects for psychological distress and sleep quality, and (3) non-attachment almost fully mediated treatment effects for FMS symptomatology and pain perception. Average daily time spent in meditation was found to be a significant predictor of changes in all outcome variables. Conclusions. Meditation awareness training may be a suitable treatment for adults with FMS and appears to ameliorate FMS symptomatology and pain perception by reducing attachment to self. (shrink)

Doxastic normativism is the thesis that norms are constitutive of or essential to belief, such that no mental state not subject to those norms counts as a belief. A common normativist view is that belief is essentially governed by a norm of truth. According to Krister Bykvist and Anandi Hattiangadi, truth norms for belief cannot be formulated without unpalatable consequences: they are either false or they impose unsatisfiable requirements on believers. I propose that we construe the fundamental norm of belief (...) as a knowledge norm, rather than a truth norm. I argue that a specific kind of knowledge norm—one that has a subject's obligation to believe that p depend on her being in a position to know that p—might avoid the well-known formulation problems with truth norms. (shrink)

Normativists about belief hold that belief formation is essentially rule- or norm-guided. On this view, certain norms are constitutive of or essential to belief in such a way that no mental state not guided by those norms counts as a belief, properly construed. In recent influential work, Kathrin Glüer and Åsa Wikforss develop novel arguments against normativism. According to their regress of motivations argument, not all belief formation can be rule- or norm-guided, on pain of a vicious infinite regress. I (...) argue that the regress of motivations argument is unsuccessful: an appeal to the notion of blind rule-following, drawn from a plausible interpretation of Ludwig Wittgenstein’s remarks on rule-following, stops the regress of motivations in its tracks. (shrink)

Idealist philosophers have traditionally tried to defend their views by appealing to the claim that nonmental reality is inconceivable. A standard response to this inconceivability claim is to try to show that it is only plausible if one blurs the fundamental distinction between consciousness and its object. I try to rehabilitate the idealistic argument by presenting an alternative formulation of the idealist’s basic inconceivability claim. Rather than suggesting that all objects are inconceivable apart from consciousness, I suggest that it is (...) impossible to conceive of any such object as genuinely existent. This thesis is lent credence by the fact that only in reflective self-consciousness is existence a phenomenological datum. Not only is it the case that we are not ever aware of an object as existing, we do not have a clear understanding of what it would be like to have such an awareness. If this is true, then we have reason to believe that while consciousness exists, the objects of consciousness cannot exist. (shrink)

Many population axiologies avoid the Repugnant Conclusion by endorsing Superiority: some number of great lives is better than any number of mediocre lives. But as Nebel shows, RC follows from the Intrapersonal Repugnant Conclusion: a guaranteed mediocre life is better than a sufficiently small probability of a great life. This result is concerning because IRC is plausible. Recently, Kosonen has argued that IRC can be true while RC is false if small probabilities are discounted to zero. This article details the (...) unique problems created by combining Superiority with discounting. The resultant view, Superiority Discounting, avoids the Repugnant Conclusion only at the cost of the Preposterous Conclusion: near-certain hell for arbitrarily many people is better than near-certain heaven for arbitrarily many people. (shrink)